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Postdoctoral Researcher or PhD Candidate in Chemistry (Enzymes)

vor einem Jahr
Aalto University
Postdoctoral Researcher or PhD Candidate in Chemistry (Enzymes)
Aalto University
Our goal is to fearlessly lead the way and take part in open-minded and creative development of both Finnish society and the international academic community.
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Veröffentlicht: vor einem Jahr
Bewerbungsschluss: Offen
Standort: Espoo, Finnland
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Postdoctoral Researcher or PhD Candidate in Chemistry (Enzymes)

Aalto University is a community of bold thinkers where science and art meet technology and business. We are committed to identifying and solving grand societal challenges and building an innovative future. Aalto University has six schools with nearly 20 000 students and more than 400 professors. Our campuses are located in Espoo and Helsinki, Finland.

Aalto University School of Chemical Engineering looking for a highly motivated

Postdoctoral Researcher or PhD Candidate, with strong knowledge in mechanistic chemistry / enzymology

The Biochemistry group transfers biochemical processes from their natural environment to the laboratory for industrial applications. We focus on the biocatalytic conversion of chemical energy (fuel) to electricity, in order to develop advanced energy solutions. We seek to also apply the reverse process, electricity to fuel, in order to store excess electricity from renewable sources efficiently.

To achieve our goals, we keep unravelling metabolic principles and enzyme function in natural microbes (in particular anaerobic archaea), and we apply synthetic biology to create the ideal metabolisms and enzymes for our industrial applications.

Research is carried out at our excellent facilities at Aalto University, School of Chemical Engineering (http://www.bioeconomyinfra.fi/). The laboratory is situated on the main campus of Aalto University in Otaniemi within the Department of Bioproducts and Biosystems (http://bio2.aalto.fi/en/).

Job description

The goal of the project is to study archaeal enzymes and elucidate their reaction mechanisms. A focus will be on methyl-coenzyme M reductase, a nickel(I) enzyme with several post-translational modifications. Experiments will be carried out with purified enzymes in order to study function, kinetics and mechanisms. Possible projects also involve synthesis of substrate analogues, electrochemistry, or advanced spectroscopic methods (NMR, EPR).

The research project is within the mission of an industrial application, but we are currently conducting fundamental research in order to discover new chemical strategies in nature, which we intend to publish in high-level journals. 

Requirements

The eligible candidate should:

  • Have a PhD/M.Sc. in suitable field, such as organic chemistry, organometallic chemistry, biochemistry, or theoretical chemistry with the desire for laboratory work
  • Be highly committed to science, strive for excellence
  • Develop own smart ideas and think independently
  • Be able to focus on solving tough scientific problems
  • Have good written and oral communication skills in English
  • Have experience in carrying out independent research and working in a team

Skills, knowledge and interest in the following areas are highly desirable:

  • Elucidation of reaction mechanisms
  • Spectroscopic methods (HPLC, NMR, EPR, Electrochemistry)
  • Enzymology, protein purification  
  • Posttranslational modifications
  • Organometallic chemistry
  • Organic synthesis

We offer

  • High-end laboratory infrastructure and friendly colleagues
  • Opportunity to work in a newly established research group and to bring in own ideas
  • Funding for PhD (4 years) / postdoc (2 years)
  • Salary according to the salary system of Aalto University

For more information

For additional scientific information, please contact Prof. Silvan Scheller (silvan.scheller@aalto.fi), in matters related to the recruitment process, HR Coordinator Sanni Mero (sanni.mero@aalto.fi).

How to apply

The application should include the following:

  • a cover letter
  • a CV
  • a research interest description
  • a list of publications (for postdoc candidates)
  • PDF copy of candidate's M.Sc. thesis or equivalent (for PhD candidates)
  • Diploma, transcript of course records with grades (for PhD candidates)
  • names and contact details of references.

All materials should be provided in English. The application materials will not be returned.

Please send your application through the online recruitment system (link below, “Apply for this job”).

Aalto University reserves the right for justified reasons to leave the position open, to extend the application period and to consider candidates who have not submitted applications during the application period.

Weiterlesen

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