PhD position: Microscopic insights into the mechanical biology of the actin cytoskeleton in Toxoplasma gondii

Location: Ludwig-Maximilians-University Munich, Faculty of Veterinary Medicine and Faculty of Physics, Sabass Group, Munich/Martinsried, Germany. Web: https://www.biostatphys.vetmed.uni-muenchen.de/research/ 

Project description

Microscopy is an indispensable tool for studying living organisms. Recent advancements in microscopy have paved the way for groundbreaking discoveries in biology and medicine. In our research group, we are utilizing innovative microscopy techniques, to investigate fundamental biological processes.

We are currently seeking a new PhD student to join our team. Candidates should possess a Master’s degree in biophysics, nanoscience, or a related field. A strong interest in applied biophysics and a desire to specialize in biophysical measurement techniques are essential.

Our research projects focus on using advanced microscopy methods to study cell mechanics. This particular project aims to explore the mechanical properties and biological functions of the actin cytoskeleton in the protozoan parasite Toxoplasma gondii. Understanding the role of the actin cytoskeleton is vital for unraveling the mechanisms behind motility, host cell invasion, and intracellular trafficking in this organism.

Our research group is based in Munich-Martinsried and comprises a diverse team of physicists, biologists, chemists, and veterinary scientists. At our facility, we also employ cutting-edge super-resolution microscopy techniques such as STED (Stimulated Emission Depletion) and STORM (Stochastic Optical Reconstruction Microscopy), alongside our other advanced microscopy methods.

Requirements for candidates:

• A Master's degree in biophysics, nanoscience, or a related field
• Prior experience with fluorescence microscopy and cell culture
• Proficiency in English
• Demonstrated curiosity, creativity, and enthusiasm for acquiring new knowledge and skills.
• Strong motivation and the ability to work independently as well as within an international, multidisciplinary team
• Experience with super-resolution microscopy and/or cell mechanical measurement techniques, such as atomic force microscopy (AFM) or traction force microscopy (TFM), is a plus

We offer:

• Interdisciplinary research in a high-quality international scientific environment
• Opportunities for interchange and collaboration with prominent research groups within our institution and at other international research centers
• A workplace offering numerous employee benefits and a monthly salary based on Germany's doctoral pay grade E13.

Application via the Graduate School Quantitative and Molecular Biosciences Munich (QMB):

As part of QMB, you will additionally have ample opportunities for scientific exchange with world-leading scientists of various fields and develop your scientific career with lasting benefits. The international PhD training program at QMB emphasizes communication and collaboration across traditionally separate disciplines, including biochemistry, medicine, bioinformatics, experimental and theoretical biophysics, and applied mathematics.

QMB places a strong emphasis on experimental work while also encouraging students to engage in theoretical approaches to derive meaningful insights from their data. This dual focus on advanced quantitative experimentation and theoretical analysis, combined with the excellence of its participating scientists, positions QMB uniquely within the European scientific landscape.

Please note: All applications have to be submitted in English through our online application tool. Applications submitted by mail or email will not be considered.

For detailed information about our application requirements see: https://qbm.genzentrum.lmu.de/application/requirements/ 

In your application, you can select up to two research groups you are interested in. For details about research areas and participating research groups, please see: https://qbm.genzentrum.lmu.de/research/research-areas-groups/