KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.
You will work at the Division of Protein Engineering (https://www.kth.se/pro/proteineng) in the group Next Generation Protein Therapeutics (https://www.kth.se/pro/proteineng/next-generation-protein-therapeutics). The research focuses on the design and engineering of new functions and properties of natural and artificial proteins, with applications in many different areas, for example for the development of biological drugs.
A main focus is directed evolution, i.e. the use of large collections of protein variants expressed on, for example, microorganisms from which proteins with desired properties can be selected.
The work will include development and characterization of new protein-based reagents, with a long-term goal of evaluating their potential for future drugs in various disease areas such as cancer and dementia. The work will include laboratory research in protein chemistry. Examples of methods may include: selection of affinity reagent from protein libraries with for example phage display technology, production and purification of recombinant proteins, biotechnological methods for analysis of purity, secondary structure, heat stability, biomolecular interactions, cell binding, etc. For more information about our research see: https://www.kth.se/pro/proteineng/next-generation-protein-therapeutics. This postdoctoral position is a full-time employed position for one year with a possible one-year extension.
Applicants must have a PhD in the subject.
When selecting the applicants, the research expertise will be assessed as well as the ability to:
Documented experience in protein engineering methodology is required. Theoretical knowledge of combinatorial protein engineering, including protein library design, is considered a distinct advantage. Experience with FACS, cell assays, recombinant protein production and purification (including affinity chromatography and HPLC) as well as biosensor assays (e.g. SPR-based), is also important.
Trade union representatives
You will find contact information to trade union representatives at KTH's webbpage.
The application should consist of:
1. Curriculum vitae
2. Transcripts from university/university
3. College Brief description of why the applicant is interested in the position.
4. Contact information for a couple of references.
Log into KTH's recruitment system in order to apply to this position. You are the main responsible to ensure that your application is complete according to the ad.
Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).
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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.
|Title||Post doctor in next-generation targeted protein therapeutics|
|Employer||KTH Royal Institute of Technology|
|Job location||Valhallavägen 79, 100 44 Stockholm|
|Published||März 19, 2019|
|Application deadline||Mai 6, 2019|
|Job type||Post Doc  |
|Fields||Biotechnologie,   Biochemie,   Bioingenieurwesen  |