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Duration of Contract Temporary employment with option for permanent position
Temporary Employment 1 year
Your Responsibilities
Active involvement in research and teaching
Culture, maintenance, and differentiation of pluripotent stem cells into cardiac cell types (e.g., cardiomyocytes, endothelial cells) as well as generation and culture of cell aggregates in 3D (e.g., organoids, engineered heart tissues)
Preparation of tissues (cell or nuclear isolation) and cell culture samples for histological, molecular biological, and functional analyses (e.g., protein, RNA, epigenetics, immunostaining, Ca-imaging).
Isolation and culture of primary cells and standard cell lines; stimulation and genetic modifications (e.g., with CRISPR/Cas9); preparation of tissues (cell or nucleus isolation) and cell culture samples for histological, molecular biological, and functional investigations (e.g., protein, RNA, epigenetics, immunostaining, Ca imaging)
Sorting and analysis of specific cell populations using flow cytometry (FACS)
Preparation of next-generation sequencing libraries (bulk and single-cell; e.g., RNA-seq, ATAC-seq, CUT&Tag, CUT&RUN, HiC, Multiome)
Conducting molecular biology standard experiments (e.g., Western Blot, qPCR)
Independent documentation, analysis, and processing of experimental data; development of standard protocols; training of new personnel
Preparation of reagents, apparatus, and working materials for laboratory exercises (pharmacy studies); co-supervision of students
General administrative tasks (e.g., ordering and keeping records of chemicals/consumables, equipment maintenance and servicing, obtaining quotes)
Your Profile
Matura and training as a biological laboratory technician, or a bachelor’s degree in a relevant field (e.g., molecular biology, cell biology, pharmacy), or other equivalent qualifications
At least 2 years of experience in:
Cell culture and sterile working methods
Analytical standard methods (e.g., Western Blot, qPCR, immunostaining, microscopy)
Planning, execution, evaluation, and presentation of experiments
Differentiation of pluripotent stem cells into cardiac (e.g., cardiomyocytes, endothelial cells) or other derived cell types; experience in 3D cell culture (e.g., organoids, engineered heart tissue (desirable)
Tissue preparation and flow cytometry (FACS) (desirable)
Preparation of sequencing libraries in bulk and/or single cells (e.g., RNAseq, ATAC-seq, CUT&RUN, CUT&Tag, HiC, scRNA-seq, Multiome, scATAC-seq) (desirable)
Experience in working with students and mentoring new staff (desirable)
Very good English skills
Good IT skills (Office); additional IT skills (Prism, R) desirable
Analytical thinking, problem-solving skills, thoroughness and precision
Independent and structured work, team spirit, strong communication skills
Pedagogical skills and willingness to continue education
Self-motivation and enjoyment of scientific work
We offer an annual gross salary of at least € 43,838.20 for a fulltime position. An overpayment based on qualification and experience is possible.
We Offer
Meaning: We offer meaningful work for the world of tomorrow.
Our internal continuing education program is as colorful as the university itself.
Collaboration: With us, you'll find interdisciplinary, cross-professional opportunities to work together.
Benefits: Of course, there are all the usual benefits, from A "access to healthcare services" to Z "Zero emission goal".
Diversity: Besides our various scientific fields and their related issues, we offer a working environment in which diversity and inclusion are lived.
Flexibility: We demonstrate flexibility not only with the various working time models but also through the offers for the compatibility of family and career.
About us
At the University of Graz, 4700 employees work together on future questions and solutions for the world of tomorrow. Our students and researchers take on the major challenges of society and share their knowledge. We work for tomorrow. Be part of it!
The research at the department of Pharmacology and Toxicology is dedicated to a variety of exciting topics to understand both disease mechanisms and physiological processes at the cellular and molecular level. Our broad research interests span several areas, including the molecular mechanisms of cardiovascular disease, kidney disease, inflammatory processes, various aspects of obesity-related health risks, signaling in the vasculature and degenerative joint disease.
The common goal of our international team of scientists from different disciplines is to gain an in-depth understanding of disease mechanisms to develop innovative approaches for prevention, diagnosis and therapy.
Contact
If you have questions, please contact Prof. Sebastian Preissl I [email protected]
The University of Graz strives to increase the proportion of women in particular in management and faculty positions and therefore encourages qualified women to apply. In the event of underrepresentation, women with equal qualifications are generally given priority for admission. We welcome applications from persons with disabilities who meet the requirements of the advertised position.
Please note that in order to comply with the applicable data protection regulations, we can only accept applications via our web-based applicant tool for this vacant position.
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